Biochemistry Questions Biochemistry Questions / Discuss the significance of screening programs for Chlamydia trachomatis, considering the asymptomatic nature of the infection in many individuals. What are the challenges in treating Chlamydia due to its unique characteristics?

Chlamydia infection is frequently asymptomatic. Many infected individuals are not aware they are infected, and so would not normally get tested.

Asymptomatic individuals are more likely to transmit the infection to others through unprotected sexual contact.

Many commonly used antibiotics are ineffective against Chlamydia trachomatis, due to the absence of peptidoglycan (so beta-lactams don’t work). Other antibiotics, such as tetracycline and doxycycline are effective but have adverse side effects.