Biochemistry Questions / Explain the role of Pattern Recognition Receptors (PRRs) in the innate immune system and how they contribute to the recognition of pathogens. Provide examples of microbe-associated molecular patterns (MAMPs) recognized by PRRs.

Pattern recognition receptors (PRRs) are important in the innate immune response, allowing pathogens to be recognised. Microbe associated molecular patterns (Mamps) are conserved structures found across a wide range of pathogens, and include LPS, dsRNA, and lipoteichoic acid. As these patterns are found almost exclusively on pathogens, the immune system can mount a response while reducing the risk of targeting a self-cell.