Biochemistry Questions Biochemistry Questions / Explain the mechanism of action of aspirin as an anti-inflammatory drug and how it differs from other NSAIDs.

Aspirin is an NSAID, inhibiting COX1. This reduces the production of prostaglandins, suppressing the inflammatory response. Aspirin is an irreversible (suicide) inhibitor of COX1, and so enzymes must be resynthesised to terminate its action.